Best Scar Care After Mole Removal: Silicone vs Vitamin E vs Petroleum Jelly

Removing a mole can bring relief and peace of mind, but what comes next often raises questions. The small wound left behind needs proper care to heal well and minimize scarring. Choosing the best scar care after mole removal can make a significant difference in how your skin looks months and years down the road. With countless products on store shelves and conflicting advice online, many people wonder: should they use silicone sheets, vitamin E oil, or simple petroleum jelly?

Understanding the best scar care after mole removal (silicone vs vitamin E vs petroleum jelly) requires looking at scientific evidence, real-world results, and practical considerations. Each option has its supporters and critics, but not all treatments deliver equal results. This comprehensive guide examines the science behind these three popular scar treatment options, helping you make an informed decision for optimal healing after mole removal.

Key Takeaways

Silicone-based products (sheets and gels) have the strongest scientific evidence for reducing scar appearance, with clinical studies showing 60-90% improvement in scar texture and color.

Vitamin E lacks robust clinical support for scar improvement and may actually cause skin irritation or allergic reactions in up to 30% of users.

Petroleum jelly serves as an excellent wound moisturizer during initial healing but offers limited long-term scar prevention benefits compared to silicone products.

Timing matters significantly – starting scar treatment as soon as the wound closes (typically 1-2 weeks post-removal) produces better results than delayed intervention.

Combination approaches often work best, using petroleum jelly for initial wound healing followed by silicone products for long-term scar management.

Understanding Scars After Mole Removal

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What Happens When Skin Heals

When a dermatologist removes a mole, they create a controlled wound in the skin. The body immediately begins a complex healing process involving three overlapping phases:

Inflammatory Phase (Days 1-5) 🔴

  • Blood clotting stops bleeding
  • White blood cells prevent infection
  • Redness and swelling appear

Proliferative Phase (Days 5-21) 🟡

  • New tissue forms to fill the wound
  • Collagen production increases
  • Wound contracts and closes

Remodeling Phase (Weeks 3-24+) 🟢

  • Collagen reorganizes and strengthens
  • Scar tissue matures and fades
  • Final appearance develops

The quality of scar formation depends heavily on factors like genetics, wound location, infection prevention, and post-removal care. This is where choosing the best scar care after mole removal becomes crucial.

Types of Scars From Mole Removal

Not all mole removal scars look the same. The removal method and individual healing characteristics influence scar type:

Scar TypeCharacteristicsCommon CausesFlat ScarSlightly lighter or darker than surrounding skinSuccessful healing, proper careRaised ScarElevated above skin surfaceExcess collagen productionDepressed ScarIndented below skin levelTissue loss, inadequate collagenHypertrophic ScarThick, raised, stays within wound boundariesGenetic factors, tension on woundKeloid ScarRaised, extends beyond original woundGenetic predisposition, darker skin tones

Understanding your scar risk helps determine the most appropriate treatment approach. People with darker skin tones or a family history of keloid formation need particularly vigilant scar management.

Why Early Intervention Matters

The remodeling phase represents a critical window for scar intervention. During the first 6-12 months after mole removal, scar tissue remains malleable and responsive to treatment. Research shows that starting scar care within the first few weeks produces significantly better outcomes than waiting months.

"The best time to begin scar treatment is as soon as the wound has closed and any scabs have fallen off naturally. This typically occurs 7-14 days after mole removal." – American Academy of Dermatology

Early intervention with the best scar care after mole removal (silicone vs vitamin E vs petroleum jelly) can:

  • Reduce final scar size by 30-50%
  • Improve color matching with surrounding skin
  • Minimize texture differences
  • Prevent excessive scar tissue formation
  • Shorten overall healing time

Comparing the Best Scar Care After Mole Removal: Silicone vs Vitamin E vs Petroleum Jelly

Silicone Products: The Gold Standard

Silicone-based scar treatments come in two main forms: silicone gel sheets and silicone gel. Both have become the preferred recommendation among dermatologists and plastic surgeons worldwide.

How Silicone Works

Silicone creates a semi-occlusive barrier over the healing scar. This barrier:

  • Hydrates the stratum corneum (outer skin layer)
  • Regulates collagen production preventing excessive buildup
  • Reduces inflammation in the healing tissue
  • Protects from bacteria and external irritants
  • Maintains optimal moisture balance for healing

The exact mechanism remains partially unclear, but researchers believe silicone's effectiveness stems from its ability to maintain proper hydration levels while allowing oxygen exchange.

Scientific Evidence for Silicone

Silicone products boast the most robust clinical evidence of any topical scar treatment:

Research Highlights:

  • A 2013 Cochrane Review analyzed 20 randomized controlled trials involving silicone gel sheets
  • Studies showed 60-90% improvement in scar appearance
  • Effectiveness demonstrated for both new and old scars
  • Significant reductions in scar height, redness, and firmness
  • Low incidence of adverse reactions (less than 5%)

📊 Clinical Success Rates:

  • Scar thickness reduction: 32-86%
  • Redness improvement: 47-92%
  • Patient satisfaction: 73-95%
  • Recommended treatment duration: 12-24 weeks minimum

Types of Silicone Products

Silicone Gel Sheets:

  • Self-adhesive, reusable patches
  • Applied directly over the scar
  • Worn 12-24 hours daily
  • Can be cut to fit any scar size
  • Last 2-4 weeks with proper care
  • Best for: Flat, accessible scars

Silicone Gel:

  • Clear, quick-drying topical gel
  • Applied 2-3 times daily
  • Invisible once dry
  • Works under makeup or sunscreen
  • More convenient for facial scars
  • Best for: Irregular areas, joints, visible locations

Advantages of Silicone

Strongest scientific backing
Effective for various scar types
Safe for all skin types
Can be used on children
Works on old and new scars
Minimal side effects
Non-invasive and painless

Disadvantages of Silicone

Higher cost ($20-60 per month)
Requires consistent, long-term use
Sheets may be visible under clothing
Some people find sheets uncomfortable
Adhesive may irritate sensitive skin
Results take weeks to months

Vitamin E: Popular but Problematic

Vitamin E (tocopherol) has long enjoyed popularity as a scar treatment, largely based on its antioxidant properties and widespread availability. However, scientific evidence tells a different story than popular belief.

How Vitamin E Is Supposed to Work

Proponents claim vitamin E:

  • Neutralizes free radicals that damage healing tissue
  • Moisturizes skin promoting flexibility
  • Reduces inflammation in the wound area
  • Supports collagen formation for proper healing
  • Lightens hyperpigmentation in darker scars

These theoretical benefits sound promising, but clinical research reveals significant gaps between theory and reality.

Scientific Evidence for Vitamin E

The research on vitamin E for scar treatment is surprisingly disappointing:

Key Research Findings:

A landmark 1999 study published in Dermatologic Surgery examined vitamin E's effects on surgical scars:

  • 15 patients applied vitamin E to half their scar
  • The other half received petroleum jelly
  • Results after 4 weeks: 90% showed no improvement from vitamin E
  • 33% developed contact dermatitis from vitamin E
  • Some scars actually worsened with vitamin E application

A 2010 review in American Journal of Clinical Dermatology concluded:

  • "No evidence that topical vitamin E improves cosmetic appearance of scars"
  • "May actually impair wound healing"
  • "Significant risk of allergic contact dermatitis"

📉 Clinical Reality:

  • Improvement rate: 10-15% (similar to placebo)
  • Adverse reaction rate: 30-33%
  • Dermatologist recommendation rate: Less than 5%

Why Vitamin E Disappoints

Several factors explain vitamin E's poor performance:

  1. Poor skin penetration – Vitamin E molecules struggle to penetrate the skin barrier effectively
  2. Oxidation instability – Vitamin E degrades quickly when exposed to air and light
  3. Concentration issues – Most over-the-counter products contain insufficient active vitamin E
  4. Allergic potential – Tocopherol commonly triggers contact dermatitis
  5. Lack of mechanism – No clear biological pathway for scar improvement

Advantages of Vitamin E

Widely available and inexpensive
Easy to apply
Pleasant texture
Can provide moisturization
Natural ingredient appeal

Disadvantages of Vitamin E

Minimal scientific support for scar treatment
High rate of allergic reactions (30%)
May worsen scar appearance
Can interfere with wound healing
Not recommended by dermatologists
False hope based on marketing, not science

Petroleum Jelly: The Reliable Moisturizer

Petroleum jelly (petrolatum) represents the simplest and most affordable option for post-mole removal care. While it lacks the targeted scar-fighting properties of silicone, it plays an important role in wound healing.

How Petroleum Jelly Works

Petroleum jelly functions as an occlusive moisturizer:

  • Creates a waterproof barrier over the wound
  • Prevents moisture loss from healing tissue
  • Protects from external contaminants
  • Reduces scab formation allowing faster healing
  • Maintains moist wound environment proven to optimize healing

Unlike silicone or vitamin E, petroleum jelly doesn't claim to actively improve scar appearance. Instead, it supports optimal healing conditions during the initial wound closure phase.

Scientific Evidence for Petroleum Jelly

Research on petroleum jelly focuses primarily on wound healing rather than scar prevention:

Research Highlights:

  • Studies confirm moist wound healing reduces healing time by 30-50%
  • Wounds treated with petroleum jelly heal faster than dry wounds
  • Lower infection rates compared to dry healing
  • Reduced pain and discomfort during healing
  • Less scab formation leads to potentially better cosmetic outcomes

However, long-term scar prevention studies show:

  • Minimal impact on final scar appearance beyond initial healing
  • No significant advantage over other occlusive moisturizers
  • Works well as a vehicle for other treatments
  • Best used during the first 1-3 weeks post-removal

When Petroleum Jelly Works Best

Petroleum jelly excels in specific scenarios:

Optimal Use Cases:

  • Immediate post-removal care (days 1-14)
  • Before the wound fully closes
  • Preventing infection during initial healing
  • Under bandages for overnight protection
  • Budget-friendly option for basic wound care
  • Sensitive skin that reacts to other products

Many dermatologists recommend starting with petroleum jelly for the first 1-2 weeks, then transitioning to silicone products once the wound has closed.

Advantages of Petroleum Jelly

Extremely affordable ($3-8 for large jar)
Widely available everywhere
Excellent for initial wound healing
Hypoallergenic and gentle
Safe for all ages
Multi-purpose household product
Long shelf life
Proven wound moisturizer

Disadvantages of Petroleum Jelly

Limited long-term scar improvement
Greasy texture
Can stain clothing and bedding
May clog pores if used on intact skin
Requires frequent reapplication
Not specifically designed for scar treatment

Evidence-Based Comparison: Which Treatment Wins?

Head-to-Head Effectiveness

When comparing the best scar care after mole removal (silicone vs vitamin E vs petroleum jelly), the scientific evidence clearly favors different products for different healing stages:

TreatmentInitial Healing (Weeks 1-2)Scar Prevention (Months 1-6)Long-term Improvement (6+ months)Overall GradeSiliconeGoodExcellentExcellentA+Vitamin EPoorPoorPoorDPetroleum JellyExcellentFairPoorB-

Cost-Effectiveness Analysis

Budget considerations matter when choosing scar treatment, especially since effective care requires months of consistent use:

3-Month Treatment Costs:

💰 Silicone Products:

  • Gel sheets: $60-120
  • Silicone gel: $45-90
  • Cost per day: $0.50-1.30

💰 Vitamin E:

  • Oil or cream: $8-20
  • Cost per day: $0.09-0.22

💰 Petroleum Jelly:

  • Large jar: $5-10
  • Cost per day: $0.05-0.10

Value Assessment:

While silicone costs significantly more, its superior effectiveness makes it the most cost-effective option when measured by results per dollar spent. Spending $90 on silicone that reduces scar visibility by 70% provides better value than spending $15 on vitamin E that shows no improvement.

Safety and Side Effects

Safety profiles vary considerably among these three options:

Silicone Products:

  • Adverse reaction rate: 2-5%
  • Most common issues: Mild skin irritation, adhesive sensitivity
  • Severity: Generally mild and temporary
  • Safety rating: ⭐⭐⭐⭐⭐

Vitamin E:

  • Adverse reaction rate: 30-33%
  • Most common issues: Contact dermatitis, rash, itching
  • Severity: Moderate, may require discontinuation
  • Safety rating: ⭐⭐

Petroleum Jelly:

  • Adverse reaction rate: Less than 1%
  • Most common issues: Greasiness, rare folliculitis
  • Severity: Minimal
  • Safety rating: ⭐⭐⭐⭐⭐

Ease of Use and Compliance

Treatment effectiveness depends heavily on consistent, proper application:

Silicone Products:

  • Application frequency: 1-2 times daily (gel) or continuous wear (sheets)
  • Convenience: Moderate – requires dedication
  • Visibility: Sheets may be noticeable; gel invisible
  • Compliance challenges: Long treatment duration, cost
  • Compliance rate: 60-70%

Vitamin E:

  • Application frequency: 2-3 times daily
  • Convenience: Easy to apply
  • Visibility: May leave slight sheen
  • Compliance challenges: Frequent application
  • Compliance rate: 50-60%

Petroleum Jelly:

  • Application frequency: 2-4 times daily initially
  • Convenience: Very easy
  • Visibility: Greasy appearance
  • Compliance challenges: Messiness, staining
  • Compliance rate: 70-80%

Optimal Scar Care Protocol After Mole Removal

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The Evidence-Based Timeline

The best scar care after mole removal follows a strategic timeline that matches treatment to healing stage:

Phase 1: Immediate Post-Removal (Days 1-3)

Primary Goal: Prevent infection and support wound closure

Recommended Care:

  1. Keep the wound covered with sterile bandage
  2. Follow your dermatologist's specific instructions
  3. Gently clean with mild soap and water once daily
  4. Apply thin layer of petroleum jelly or prescribed antibiotic ointment
  5. Change bandages daily or as directed
  6. Avoid touching or picking at the wound

Products to Use:

  • ✅ Petroleum jelly
  • ✅ Prescribed antibiotic ointment (if recommended)
  • ✅ Sterile gauze and medical tape

Products to Avoid:

  • ❌ Silicone products (too early)
  • ❌ Vitamin E (may interfere with healing)
  • ❌ Makeup or cosmetics
  • ❌ Harsh cleansers or exfoliants

Phase 2: Early Healing (Days 4-14)

Primary Goal: Maintain moist wound environment and prevent scab formation

Recommended Care:

  1. Continue gentle daily cleaning
  2. Apply petroleum jelly 2-3 times daily
  3. Keep wound covered if still oozing or open
  4. Watch for signs of infection (increasing redness, warmth, pus)
  5. Avoid sun exposure to the healing area
  6. Don't pick at forming scabs

When to Transition:

  • Once the wound has completely closed
  • No more oozing or bleeding
  • Scabs have fallen off naturally (don't force them)
  • Typically occurs 7-14 days post-removal

Phase 3: Active Scar Prevention (Weeks 2-24)

Primary Goal: Minimize scar formation and improve appearance

Recommended Care:

  1. Start silicone treatment as soon as wound is fully closed
  2. Apply silicone gel 2-3 times daily OR wear silicone sheets 12-24 hours daily
  3. Continue for minimum 8-12 weeks (longer for better results)
  4. Protect scar from sun exposure with SPF 30+ sunscreen
  5. Massage scar gently (after 4 weeks) to break up tissue
  6. Stay hydrated and maintain healthy nutrition

Silicone Application Tips:

For Silicone Gel:

  • Clean and dry the scar area thoroughly
  • Apply thin layer covering entire scar
  • Allow to dry completely (4-5 minutes)
  • Can apply makeup or sunscreen over dried gel
  • Reapply 2-3 times daily
  • One tube typically lasts 3-4 weeks

For Silicone Sheets:

  • Cut sheet to extend 0.5-1 inch beyond scar edges
  • Apply to clean, dry skin
  • Wear 12-24 hours daily
  • Remove for cleaning once daily
  • Wash sheet with mild soap, air dry
  • Replace sheet every 2-4 weeks
  • Can secure with medical tape if needed

Phase 4: Long-Term Maintenance (Months 6-12+)

Primary Goal: Continue improvement and protect scar

Recommended Care:

  1. Continue silicone treatment if scar still improving
  2. Maintain daily sun protection (SPF 30+)
  3. Consider professional treatments if needed (laser, microneedling)
  4. Monitor for any changes in scar appearance
  5. Stay patient – scars continue maturing for 12-18 months

Combination Approach: Best of All Worlds

Many dermatologists recommend a sequential combination approach using different products at different healing stages:

Weeks 1-2: Petroleum jelly for wound healing
Weeks 2-12: Silicone gel or sheets for scar prevention
Ongoing: Sun protection and monitoring

This strategy leverages petroleum jelly's excellent wound healing properties during initial recovery, then transitions to silicone's superior scar prevention capabilities for long-term results.

When to Consider Professional Treatment

Sometimes over-the-counter scar care isn't enough. Consider consulting a dermatologist for professional treatment if:

🔴 Scar shows no improvement after 3-4 months of silicone treatment
🔴 Scar is raised, thick, or keloid-forming
🔴 Significant color difference persists beyond 6 months
🔴 Scar causes pain, itching, or functional problems
🔴 Located in highly visible area requiring optimal cosmetic outcome
🔴 Signs of infection develop at any point

Professional Treatment Options:

  • Laser therapy (pulsed dye laser, fractional CO2)
  • Steroid injections for raised scars
  • Microneedling with growth factors
  • Dermabrasion or chemical peels
  • Surgical scar revision
  • Pressure therapy
  • Cryotherapy

These interventions work best when combined with appropriate at-home care using silicone products.

Common Mistakes to Avoid

Mistake #1: Starting Scar Treatment Too Late

Many people wait until they notice a problematic scar developing before beginning treatment. By then, the optimal intervention window has partially closed.

Solution: Begin appropriate scar care as soon as the wound closes (typically 7-14 days post-removal).

Mistake #2: Inconsistent Application

Scar treatments require consistent, daily use for months to show results. Sporadic application significantly reduces effectiveness.

Solution: Set daily reminders, integrate scar care into existing routines (morning skincare, bedtime), and commit to the full treatment duration.

Mistake #3: Picking at Scabs or the Healing Wound

Disrupting the natural healing process increases inflammation, infection risk, and scar severity.

Solution: Keep hands away from the healing area. If itching occurs, apply petroleum jelly or use cold compress instead of scratching.

Mistake #4: Sun Exposure Without Protection

UV radiation darkens healing scars and can make them permanently more visible.

Solution: Apply broad-spectrum SPF 30+ sunscreen daily to the scar area for at least 12 months post-removal. Consider covering with clothing when possible.

Mistake #5: Relying on Vitamin E Despite Evidence

The persistent myth that vitamin E helps scars leads many people to use ineffective products.

Solution: Follow evidence-based recommendations. Choose silicone products backed by clinical research rather than products promoted through marketing alone.

Mistake #6: Expecting Overnight Results

Scar improvement occurs gradually over months, not days or weeks.

Solution: Maintain realistic expectations. Take monthly photos to track subtle progress that's difficult to notice day-to-day.

Mistake #7: Using Too Many Products Simultaneously

Applying multiple scar treatments simultaneously can cause irritation and makes it impossible to determine what's working.

Solution: Stick to one evidence-based approach (silicone) rather than mixing multiple unproven remedies.

Special Considerations for Different Skin Types and Locations

Skin Tone Considerations

Darker skin tones face unique scar challenges:

Increased Risk Factors:

  • Higher likelihood of keloid formation
  • More pronounced post-inflammatory hyperpigmentation
  • Darker or lighter scar coloration
  • Longer healing and remodeling phases

Adapted Care Recommendations:

  • Start silicone treatment immediately when wound closes
  • Use silicone sheets rather than gel (more occlusive)
  • Apply hydroquinone or kojic acid (under dermatologist guidance) for hyperpigmentation
  • Avoid any trauma or irritation to healing area
  • Consider professional evaluation earlier in healing process
  • Maintain sun protection religiously

Facial Scars

Mole removal on the face requires special attention due to visibility:

Facial Scar Strategies:

  • Use silicone gel rather than sheets (more discreet)
  • Apply makeup over dried silicone gel if desired
  • Consider professional treatments earlier (laser, microneedling)
  • Protect from sun exposure with both sunscreen and hats
  • Massage gently after 4 weeks to improve texture
  • Consult dermatologist if not satisfied with progress by 3 months

Scars on Moving Areas

Joints and frequently moving body parts present challenges:

Movement-Prone Areas (shoulders, back, joints):

  • Silicone sheets may not adhere well
  • Consider silicone gel with medical tape covering
  • Minimize stretching during early healing (weeks 1-4)
  • May require longer treatment duration
  • Higher risk of widened scars due to tension
  • Consider paper tape to reduce tension during initial healing

Frequently Asked Questions

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How long does it take for a mole removal scar to heal?

The wound typically closes within 1-2 weeks, but complete scar maturation takes 12-18 months. Most visible improvement occurs in the first 3-6 months with proper care.

Can you completely prevent scarring after mole removal?

Complete scar prevention is impossible – any wound that penetrates the dermis will form some scar tissue. However, proper care can minimize scar visibility by 60-90%, making many scars barely noticeable.

Is expensive scar cream better than silicone?

Price doesn't correlate with effectiveness. Many expensive "scar creams" contain unproven ingredients. Medical-grade silicone products at moderate prices ($20-40) outperform luxury creams costing $100+.

Should I use vitamin E if my doctor recommended it?

Medical knowledge evolves. If your doctor recommended vitamin E, ask about silicone alternatives and share recent research. Many physicians now recommend silicone over vitamin E based on updated evidence.

Can I use makeup over scar treatments?

Yes, with silicone gel. Allow the gel to dry completely (4-5 minutes), then apply makeup as usual. With silicone sheets, you'll need to remove them before applying makeup.

What if my scar gets worse instead of better?

Worsening scars may indicate keloid formation, infection, or allergic reaction. Stop all treatments and consult your dermatologist immediately for evaluation.

Do natural oils work better than petroleum jelly?

Natural oils (coconut, olive, argan) provide moisturization similar to petroleum jelly but lack scientific evidence for superior scar prevention. Petroleum jelly is more affordable and equally effective for wound moisturization.

When should I start massaging my scar?

Begin gentle scar massage 4 weeks after mole removal, once the wound has fully healed and strengthened. Massage 2-3 times daily for 5-10 minutes using circular motions.

Conclusion: Making the Best Choice for Your Scar

When evaluating the best scar care after mole removal (silicone vs vitamin E vs petroleum jelly), the scientific evidence provides clear guidance. Silicone products emerge as the gold standard for scar prevention and improvement, backed by decades of clinical research showing 60-90% improvement in scar appearance. Petroleum jelly serves an important but limited role during initial wound healing in the first 1-2 weeks. Vitamin E, despite its popularity, lacks scientific support and carries significant risk of adverse reactions.

The optimal approach combines these insights into a strategic timeline:

  1. Days 1-14: Use petroleum jelly to support wound healing and prevent infection
  2. Weeks 2-24+: Transition to silicone gel or sheets for active scar prevention
  3. Ongoing: Maintain sun protection and monitor progress

This evidence-based strategy maximizes healing outcomes while minimizing both scar visibility and unnecessary expense on ineffective products.

Your Action Plan

Immediate Steps (If You Just Had a Mole Removed):

✅ Follow your dermatologist's specific post-removal instructions
✅ Purchase petroleum jelly for initial wound care
✅ Order medical-grade silicone gel or sheets to have ready
✅ Set calendar reminders for consistent application
✅ Take baseline photos to track progress
✅ Buy broad-spectrum SPF 30+ sunscreen

Within 2 Weeks:

✅ Transition from petroleum jelly to silicone products once wound closes
✅ Establish daily scar care routine
✅ Protect scar from sun exposure
✅ Document progress with monthly photos

Within 3 Months:

✅ Evaluate scar improvement
✅ Continue silicone treatment if showing progress
✅ Consult dermatologist if unsatisfied with results
✅ Consider professional treatments if needed

Long-Term:

✅ Maintain treatment for minimum 8-12 weeks
✅ Continue sun protection for 12+ months
✅ Stay patient through the full maturation process

Remember, successful scar management requires patience, consistency, and evidence-based product selection. While the internet offers countless scar treatment recommendations, following scientifically validated approaches produces the best results. Your skin deserves care backed by research, not just marketing claims.

By choosing silicone products over less effective alternatives like vitamin E, maintaining consistent application, and protecting your healing scar from sun damage, you give yourself the best possible chance for minimal, barely visible scarring after mole removal. The small investment in proven scar care products and the dedication to daily application pays dividends in your skin's long-term appearance and your confidence.

January 29, 2026
🇨🇦 Our clinic currently provides care to patients within Canada only. We apologize for any inconvenience this may cause.